Wednesday, Nov. 11, 2026 · about a 5-minute read
Good morning. Yesterday brought Google buying 12 times more round-the-clock power drilled from hot rock, a robot brain that learns a chore from five demonstrations and San Antonio riders choosing between two driverless services. Today one infusion cut sky-high blood fats 63%, its maker says.
The big one
Heart Protection in One Infusion: Blood Fats Fell 63%, Its Maker Says Some people are born with a broken copy of a liver gene called ANGPTL3 and go through life with unusually low blood fats. CRISPR Therapeutics says one IV infusion of its gene editor, CTX310, switched that gene off and cut average triglycerides 63% within 30 days in 10 people whose levels were several times the healthy range, with no serious side effects tied to the drug. These are company-reported results from a small, open-label trial.
Why it matters: most heart-risk drugs are taken every day for life, and this is a one-time edit aimed at one of the blood fats behind that risk. Our odds that a one-time gene edit is approved for very high triglycerides: chance it works 70%, likely by 2033. Read it →
Yesterday on the site
The End of Aging
Baldness Fixed by Combing? An Electric Comb Regrew Nearly All Lost Hair in Mice: a team in China says a comb-shaped device pushed two gene treatments into balding skin and restored close to all the lost hair in one month, in mice.
The End of Disease
Can a Pill Slow Alzheimer's? A 1,535-Person Trial Answers Next Week: one Alzheimer's antibody cut plaque but did not slow decline, and pill and tau-drug results come Nov. 16 to 19.
Stopping Alzheimer's Before the First Symptom: A Prevention Trial Is Now Enrolling: Roche says its late-stage trial in people with early Alzheimer's brain changes but no symptoms has started enrolling.
Robots & Self-Driving
More Driverless Rides Coming: Tesla Says the Cybertruck Makes Way for Robotaxis: Musk says Tesla will stop making the Cybertruck in 2027 and build more two-seat Cybercabs in its space (secondary report).
Laundry-Folding Robots Learn From Human Hands: 78% Success vs. 27%, Its Makers Say: a Japanese robot brain that learned from people using a hand-held gripper beat rivals 78% to 27% in its lab's own ten-task test.
Skip the Traffic: A Flying Taxi Is Three of Five Steps Through FAA Approval: Joby has finished three of five FAA certification stages and targets its next formal flight tests for the first half of 2027.
Cheaper Driverless Rides Ahead? San Antonio Riders Can Now Pick Tesla or Waymo: Tesla switched on driverless rides across about 272 square miles of San Antonio, joining Waymo (secondary reports).
Robot Butlers That Learn Chores From Five Demos: 95% Success, NVIDIA Says: NVIDIA says its robot brain, trained mostly on human video, averaged 95% on its chosen tasks after five demonstrations.
Over LA Traffic by 2027: An Air Taxi Gets FAA Clearance, Its Maker Says: Archer says its air taxi holds an FAA certificate for Los Angeles demonstration flights, with passengers planned in 2027.
Thinking Machines
Solving the Data Center Problem: Data Centers in Space Are Real: a market survey counts 21 of 53 orbital-computing projects with hardware already in space.
AI's Lab Skills More Than Doubled on OpenAI's Test. Faster Medicines Are the Goal.: OpenAI's best model scored 66.7% on its own 100-task wet-lab test, up from 31.2% for a 2025-era model.
Trustworthy AI Science Speeds Up: Fermat's Proof Machine-Checked in 30 Hours, Its Maker Says: Anthropic says 1,000 copies of its newest model turned Fermat's Last Theorem into a computer-checked proof in 30 hours, down from 11 days.
Limitless Energy
Clean Power That Never Sleeps: Google Is Buying 12 Times More Hot-Rock Electricity: Fervo's first 33-megawatt hot-rock power block is running in Utah, and Google signed for 396 megawatts more from mid-2028 (company claims).
By the numbers
396 megawatts: the round-the-clock geothermal power Google is buying from Fervo, 12 times the block running now.
95%: NVIDIA's average success on its chosen robot tasks after five demonstrations, its own figure.
About 272 square miles: the San Antonio area Tesla's driverless rides now cover, roughly four and a half times Waymo's there.
30 hours: how long 1,000 AI agents took to turn Fermat's proof into one a computer checks, down from 11 days.
New on the odds board
Yesterday's posts put fresh odds on robotaxis replacing pickup trucks, a hair-regrowing comb, computers in orbit, robots that learn from human hands, an Alzheimer's pill, a flying taxi's FAA steps, A.I. lab skills, geothermal power for Google, a two-company robotaxi city, machine-checked math, catching Alzheimer's before symptoms, robot butlers taught by showing and air taxis over Los Angeles. Every milestone lives on the calculator.
On the calendar
Nov. 16 to 19: results due for an Alzheimer's pill and a tau-lowering drug.
Nov. 17: early data on Roche's inflammation-blocking Alzheimer's pill.
December: NVIDIA says the code for its robot brain arrives.
First half of 2027: Joby's target for its next formal FAA flight tests.
2027: Archer's plan for its first passengers in Los Angeles.
Mid-2028: first power from Fervo's 396-megawatt Google project.
The story we're following
Air taxis are inching toward paying riders. In one day we covered Joby finishing three of five FAA certification stages and Archer saying it holds FAA clearance for demonstration flights over Los Angeles, with passengers planned for 2027. Two companies racing through the same federal process is how a ride over traffic stops being a demo and becomes a booking.
Quote of the day
"All Diseases may by sure means be prevented or cured, not excepting even that of Old Age, and our Lives lengthened at pleasure even beyond the antediluvian Standard." — Benjamin Franklin, in a 1780 letter to the chemist Joseph Priestley. Today one infusion aimed at a heart-risk gene is a small step on his list.
Coming up
Already up this morning: one infusion that cut sky-high blood fats 63%, its maker says. The rest of today's lineup posts through the day.
Until next time
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